GOT1 Antikörper (N-Term)

Produktnummer ABIN2783280

Produktdetails anti-GOT1 Antikörper

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Ziege, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GOT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MAPPSVFAEV PQAQPVLVFK LTADFREDPD PRKVNLGVGA YRTDDCHPWV

Homologie: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against GOT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GOT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 413 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GOT1 Antikörper (ABIN2783280)

Povlsen, Løfgren, Dalgas, Birkler, Johannsen, Støttrup, Bøtker: "Protection against myocardial ischemia-reperfusion injury at onset of type 2 diabetes in Zucker diabetic fatty rats is associated with altered glucose oxidation." in: PLoS ONE, Vol. 8, Issue 5, pp. e64093, (2013) (PubMed).

Takeda, Ishida, Takahashi, Ueda: "Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from ?-ketoglutarate for vesicular loading." in: Journal of neurochemistry, Vol. 121, Issue 2, pp. 184-96, (2012) (PubMed).

Inoue, Matsumoto, Miyoshi, Kobayashi: "Elevated liver enzymes in women with a family history of diabetes." in: Diabetes research and clinical practice, Vol. 79, Issue 3, pp. e4-7, (2008) (PubMed).

Details zu GOT1

Target: GOT1 (Glutamic-Oxaloacetic Transaminase 1, Soluble (Aspartate Aminotransferase 1) (GOT1))

Andere Bezeichnung: GOT1 (GOT1 Produkte)

Synonyme: ASTQTL1 antikoerper, GIG18 antikoerper, cAspAT antikoerper, cCAT antikoerper, AST antikoerper, ISSD antikoerper, NSD antikoerper, SD antikoerper, SIALIN antikoerper, SIASD antikoerper, SLD antikoerper, xr406 antikoerper, CASPAT antikoerper, ASPARTATE AMINOTRANSFERASE antikoerper, ATAAT antikoerper, MATERNAL EFFECT EMBRYO ARREST 17 antikoerper, MEE17 antikoerper, T26C19.9 antikoerper, T26C19_9 antikoerper, aspartate aminotransferase antikoerper, aatA antikoerper, 83.t00021 antikoerper, AI789014 antikoerper, Got-1 antikoerper, Aspat antikoerper, Gaspat antikoerper, AL022787 antikoerper, FABP-pm antikoerper, Got-2 antikoerper, mAspAT antikoerper, ASPATA antikoerper, glutamic-oxaloacetic transaminase 1 antikoerper, solute carrier family 17 member 5 antikoerper, glutamic-oxaloacetic transaminase 1 homeolog antikoerper, aspartate aminotransferase antikoerper, glutamic-oxaloacetic transaminase 1, soluble antikoerper, glutamic-oxaloacetic transaminase 2 antikoerper, glutamatic-oxaloacetic transaminase 2, mitochondrial antikoerper, GOT1 antikoerper, SLC17A5 antikoerper, got1.S antikoerper, AAT antikoerper, aspC antikoerper, EHI_006080 antikoerper, AST2 antikoerper, ast2 antikoerper, got1 antikoerper, Got1 antikoerper, GOT2 antikoerper, Got2 antikoerper

Hintergrund: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enz
Alias Symbols: GIG18, ASTQTL1
Protein Interaction Partner: UBC, CHRAC1, SBDS, UBE2H, TYMS, MTAP, IDH1, HPRT1, ANXA6, ABI3BP, EGFR, TMEM120A, PC,
Protein Size: 413

Molekulargewicht: 46 kDa

Gen-ID: 2805

NCBI Accession: NM_002079, NP_002070

UniProt: P17174

Pathways: Hepatitis C, Monocarboxylic Acid Catabolic Process, Methionine Biosynthetic Process