TPM2 Antikörper (C-Term)

Produktnummer ABIN2783288

Produktdetails anti-TPM2 Antikörper

Target: TPM2 (Tropomyosin-2 (TPM2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Schwein, Schaf, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AETRAEFAER SVAKLEKTID DLEDEVYAQK MKYKAISEEL DNALNDITSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 100%, Pig: 85%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TPM2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 284 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TPM2 Antikörper (ABIN2783288)

Abdul-Hussein, Rahl, Moslemi, Tajsharghi: "Phenotypes of myopathy-related beta-tropomyosin mutants in human and mouse tissue cultures." in: PLoS ONE, Vol. 8, Issue 9, pp. e72396, (2013) (PubMed).

Tajsharghi, Ohlsson, Lindberg, Oldfors: "Congenital myopathy with nemaline rods and cap structures caused by a mutation in the beta-tropomyosin gene (TPM2)." in: Archives of neurology, Vol. 64, Issue 9, pp. 1334-8, (2007) (PubMed).

Details zu TPM2

Target: TPM2 (Tropomyosin-2 (TPM2))

Andere Bezeichnung: TPM2 (TPM2 Produkte)

Synonyme: CG4843 antikoerper, DROTROPI1 antikoerper, Dmel\\CG4843 antikoerper, Ifm(3)3 antikoerper, Ifm(3)5 antikoerper, Ifm-TmI antikoerper, TM2 antikoerper, Tm antikoerper, Tm1 antikoerper, Tm127 antikoerper, TmI antikoerper, TmII antikoerper, Tn-H antikoerper, dro Tm antikoerper, l(3)nc99Eb antikoerper, mTmI antikoerper, cb836 antikoerper, fb68h02 antikoerper, tpm4l antikoerper, wu:fb68h02 antikoerper, wu:fj63f03 antikoerper, zgc:86810 antikoerper, AMCD1 antikoerper, DA1 antikoerper, DA2B antikoerper, TMSB antikoerper, nem4 antikoerper, tpm2 antikoerper, tpm2a antikoerper, BRT-2 antikoerper, TPM3 antikoerper, NEM4 antikoerper, Tpm-2 antikoerper, Trop-2 antikoerper, Tropomyosin 2 antikoerper, Tropomyosin-2 antikoerper, tropomyosin antikoerper, tropomyosin 2 (beta) antikoerper, tropomyosin 2 L homeolog antikoerper, tropomyosin 2 antikoerper, tropomyosin 2, beta antikoerper, Tm2 antikoerper, EDI_309330 antikoerper, LOC100101174 antikoerper, tpm2 antikoerper, tpm2.L antikoerper, TPM2 antikoerper, Tpm2 antikoerper

Hintergrund: TPM2 is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers.The TPM2 gene encodes beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers (Tajsharghi et al., 2007 [PubMed 17846275]). See also TPM1 (MIM 191010), TPM3 (MIM 191030), and TPM4 (MIM 600317).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AMCD1, DA1, TMSB, DA2B, NEM4
Protein Interaction Partner: UBC, RPA3, RPA2, RPA1, HECTD1, SKIL, STAM, TPM4, TPM3, TPM1, SULT1A1, NONO, STMN1, DYNC1H1, DDX3X, DDB1, SRXN1, CPSF7, CORO1B, DSTN, SF3B2, AHCYL1, DDX46, TAF15, LRRK2, AKT1, SP1, ACTA1, S100A4, TPM2, PDLIM7, PIK3CG, RRAD, S100A2, JUN, ADRBK1, ACTB,
Protein Size: 284

Molekulargewicht: 33 kDa

Gen-ID: 7169

NCBI Accession: NM_003289, NP_003280

UniProt: P07951