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Sep 15 Antikörper (Middle Region)

SEP15 Reaktivität: Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783300
  • Target Alle Sep 15 (SEP15) Antikörper anzeigen
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Bindungsspezifität
    • 2
    • 1
    • 1
    Middle Region
    Reaktivität
    • 12
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Schwein, Zebrafisch (Danio rerio), Rind (Kuh)
    Wirt
    • 11
    • 1
    Kaninchen
    Klonalität
    • 12
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sep 15 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 2
    Western Blotting (WB)
    Sequenz
    SDKPKLFRGL QIKYVRGSDP VLKLLDDNGN IAEELSILKW NTDSVEEFLS
    Homologie
    Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SEP15. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SEP15
    Top Product
    Discover our top product SEP15 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 165 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
    Andere Bezeichnung
    SEP15 (SEP15 Produkte)
    Synonyme
    9430015P09Rik antikoerper, cb29 antikoerper, zgc:86882 antikoerper, BcDNA:SD16138 antikoerper, Dmel\\CG7484 antikoerper, Prise 8 antikoerper, Sep15 antikoerper, selenoprotein F antikoerper, CG7484 gene product from transcript CG7484-RB antikoerper, SELENOF antikoerper, Selenof antikoerper, selenof antikoerper, CG7484 antikoerper
    Hintergrund
    SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: -
    Protein Interaction Partner: METTL23, UBC, DCUN1D1, CUL3, BAMBI, XRCC6, UGGT2, UGGT1,
    Protein Size: 165
    Molekulargewicht
    15 kDa
    Gen-ID
    9403
    NCBI Accession
    NM_004261, NP_004252
    UniProt
    O60613
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