Sep 15 Antikörper (Middle Region)
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- Target Alle Sep 15 (SEP15) Antikörper anzeigen
- Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Schwein, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Sep 15 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SDKPKLFRGL QIKYVRGSDP VLKLLDDNGN IAEELSILKW NTDSVEEFLS
- Homologie
- Cow: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SEP15. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SEP15
- Top Product
- Discover our top product SEP15 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 165 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Sep 15 (SEP15) (15 KDa Selenoprotein (SEP15))
- Andere Bezeichnung
- SEP15 (SEP15 Produkte)
- Synonyme
- 9430015P09Rik antikoerper, cb29 antikoerper, zgc:86882 antikoerper, BcDNA:SD16138 antikoerper, Dmel\\CG7484 antikoerper, Prise 8 antikoerper, Sep15 antikoerper, selenoprotein F antikoerper, CG7484 gene product from transcript CG7484-RB antikoerper, SELENOF antikoerper, Selenof antikoerper, selenof antikoerper, CG7484 antikoerper
- Hintergrund
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SEP15 is a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. The gene that encodes the protein is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies in mouse suggest that this selenoprotein may have redox function and may be involved in the quality control of protein folding. This gene is localized on chromosome 1p31, a genetic locus commonly mutated or deleted in human cancers. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: METTL23, UBC, DCUN1D1, CUL3, BAMBI, XRCC6, UGGT2, UGGT1,
Protein Size: 165 - Molekulargewicht
- 15 kDa
- Gen-ID
- 9403
- NCBI Accession
- NM_004261, NP_004252
- UniProt
- O60613
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