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COQ8A Antikörper (N-Term)

COQ8A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783345
  • Target Alle COQ8A Antikörper anzeigen
    COQ8A (Coenzyme Q8A (COQ8A))
    Bindungsspezifität
    • 15
    • 8
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 52
    • 31
    • 30
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 53
    • 13
    Kaninchen
    Klonalität
    • 53
    • 13
    Polyklonal
    Konjugat
    • 26
    • 6
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COQ8A Antikörper ist unkonjugiert
    Applikation
    • 57
    • 32
    • 13
    • 13
    • 10
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    FANPRDSFSA MGFQRRFFHQ DQSPVGGLTA EDIEKARQAK ARPENKQHKQ
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CABC1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CABC1
    Top Product
    Discover our top product COQ8A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 647 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lagier-Tourenne, Tazir, López, Quinzii, Assoum, Drouot, Busso, Makri, Ali-Pacha, Benhassine, Anheim, Lynch, Thibault, Plewniak, Bianchetti, Tranchant, Poch, DiMauro, Mandel, Barros, Hirano, Koenig: "ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency." in: American journal of human genetics, Vol. 82, Issue 3, pp. 661-72, (2008) (PubMed).

  • Target
    COQ8A (Coenzyme Q8A (COQ8A))
    Andere Bezeichnung
    CABC1 (COQ8A Produkte)
    Synonyme
    ARCA2 antikoerper, CABC1 antikoerper, COQ10D4 antikoerper, COQ8 antikoerper, SCAR9 antikoerper, 4632432J16Rik antikoerper, AI462003 antikoerper, Cabc1 antikoerper, mKIAA0451 antikoerper, cabc1 antikoerper, Adck3 antikoerper, adck4 antikoerper, si:dkey-114g7.2 antikoerper, coenzyme Q8A antikoerper, aarF domain containing kinase 3 antikoerper, coenzyme Q8B antikoerper, COQ8A antikoerper, Coq8a antikoerper, coq8a antikoerper, ADCK3 antikoerper, coq8b antikoerper
    Hintergrund
    CABC1 is a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis.This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.
    Alias Symbols: ADCK3, COQ8, MGC4849, ARCA2, CABC1, SCAR9
    Protein Interaction Partner: TMEM239, REEP6, TMEM159, AGTRAP, TFIP11, RABAC1, VCP, UBC, IRAK2, IRAK1, ICT1, COQ8,
    Protein Size: 647
    Molekulargewicht
    72 kDa
    Gen-ID
    56997
    NCBI Accession
    NM_020247, NP_064632
    UniProt
    Q8NI60
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