GSTA3 Antikörper (Middle Region)
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- Target Alle GSTA3 Antikörper anzeigen
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GSTA3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR
- Homologie
- Human: 100%, Mouse: 79%, Sheep: 77%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GSTA3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GSTA3
- Top Product
- Discover our top product GSTA3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 222 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
- Andere Bezeichnung
- GSTA3 (GSTA3 Produkte)
- Synonyme
- GSTA3 antikoerper, GST antikoerper, GSTA1 antikoerper, GSTA3-3 antikoerper, GTA3 antikoerper, GSTA2 antikoerper, Gst2-3 antikoerper, Yc2 antikoerper, glutathione S-transferase alpha 3 antikoerper, glutathione S-transferase A2 antikoerper, glutathione S-transferase antikoerper, glutathione S-transferase, alpha 3 antikoerper, glutathione S-transferase Yc antikoerper, GSTA3 antikoerper, LOC474938 antikoerper, gsta3 antikoerper, Gsta3 antikoerper, LOC100328911 antikoerper
- Hintergrund
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Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
Alias Symbols: GSTA3-3, GTA3, MGC22232
Protein Interaction Partner: BAG3, APP,
Protein Size: 222 - Molekulargewicht
- 25 kDa
- Gen-ID
- 2940
- NCBI Accession
- NM_000847, NP_000838
- UniProt
- Q16772
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