PYGB Antikörper (N-Term)

Produktnummer ABIN502964

Produktdetails anti-PYGB Antikörper

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Zebrafisch (Danio rerio), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QQHYYERDPK RIYYLSLEFY MGRTLQNTMV NLGLQNACDE AIYQLGLDLE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PYGB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PYGB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 843 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PYGB

Target: PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

Andere Bezeichnung: PYGB (GPBB Produkte)

Hintergrund: PYGB is a glycogen phosphorylase found predominantly in the brain. It forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC9213, GPBB
Protein Interaction Partner: UBC, SIAH1, PYGL, PYGB, SUMO2, SUMO3, WDR61, RIC8A, OGFOD1, UBA6, UBR7, LIMD1, XPNPEP1, PLCG1, FH, NPM1, CPNE1, PSMB2, CAND1, SIRT7, MLH1, ACTN1,
Protein Size: 843

Molekulargewicht: 97 kDa

Gen-ID: 5834

NCBI Accession: NM_002862, NP_002853

UniProt: P11216

Pathways: Cellular Glucan Metabolic Process