SNAP23 Antikörper (N-Term)
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- Target Alle SNAP23 Antikörper anzeigen
- SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SNAP23 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GIKTITMLDE QKEQLNRIEE GLDQINKDMR ETEKTLTELN KCCGLCVCPC
- Homologie
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Yeast: 83%, Zebrafish: 90%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SNAP23. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SNAP23
- Top Product
- Discover our top product SNAP23 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 211 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SNAP23 (Synaptosomal-Associated Protein, 23kDa (SNAP23))
- Andere Bezeichnung
- SNAP23 (SNAP23 Produkte)
- Synonyme
- 23kDa antikoerper, AA408749 antikoerper, SNAP-23 antikoerper, Sndt antikoerper, Syndet antikoerper, HsT17016 antikoerper, SNAP23A antikoerper, SNAP23B antikoerper, XOSNAP-23 antikoerper, snap23-A antikoerper, synaptosome associated protein 23 antikoerper, synaptosome associated protein 23kDa antikoerper, synaptosomal-associated protein 23 antikoerper, synaptosome associated protein 23kDa L homeolog antikoerper, SNAP23 antikoerper, snap23 antikoerper, Snap23 antikoerper, snap23.L antikoerper
- Hintergrund
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SNAP23 is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.
Alias Symbols: HsT17016, SNAP23A, SNAP23B, SNAP-23
Protein Interaction Partner: VAMP5, SNAP23, STX11, UBC, NAPB, STX1A, FN1, ILF2, HNRNPAB, ANXA3, C12orf57, UBQLN2, SCFD1, SYNCRIP, FAM3C, YES1, STX4, SRSF1, PSAP, CEP97, CCP110, ELAVL1, WASH2P, MATR3, NSF, STX3, TLK1, SCGN, ABI2, STX6, KIF5B, STXBP5, SNAPIN, SCAMP2, SCAMP1, STX12, ABI
Protein Size: 211 - Molekulargewicht
- 23 kDa
- Gen-ID
- 8773
- NCBI Accession
- NM_003825, NP_003816
- UniProt
- O00161
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