BHMT2 Antikörper (Middle Region)

Produktnummer ABIN2783509

Produktdetails anti-BHMT2 Antikörper

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BHMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GFVDLPEYPF GLESRVATRW DIQKYAREAY NLGVRYIGGC CGFEPYHIRA

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BHMT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BHMT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 363 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BHMT2

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Andere Bezeichnung: BHMT2 (BHMT2 Produkte)

Synonyme: C81077 antikoerper, D13Ucla2 antikoerper, BHMT2 antikoerper, DKFZp469M1332 antikoerper, bhmt-2 antikoerper, betaine--homocysteine S-methyltransferase 2 antikoerper, betaine-homocysteine methyltransferase 2 antikoerper, betaine-homocysteine S-methyltransferase 2 antikoerper, S-methylmethionine--homocysteine S-methyltransferase BHMT2 antikoerper, BHMT2 antikoerper, Bhmt2 antikoerper, LOC100073266 antikoerper

Hintergrund: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ20001
Protein Interaction Partner: APP,
Protein Size: 363

Molekulargewicht: 40 kDa

Gen-ID: 23743

NCBI Accession: NM_017614, NP_060084

UniProt: Q9H2M3

Pathways: Methionine Biosynthetic Process