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POLR3B Antikörper (C-Term)

POLR3B Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Saccharomyces cerevisiae, Ziege WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783516
  • Target Alle POLR3B Antikörper anzeigen
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 27
    • 27
    • 8
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Saccharomyces cerevisiae, Ziege
    Wirt
    • 37
    • 2
    Kaninchen
    Klonalität
    • 37
    • 2
    Polyklonal
    Konjugat
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLR3B Antikörper ist unkonjugiert
    Applikation
    • 27
    • 24
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IEKVMISSNA EDAFLIKMLL RQTRRPEIGD KFSSRHGQKG VCGLIVPQED
    Homologie
    Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against POLR3B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human POLR3B
    Top Product
    Discover our top product POLR3B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1133 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yee, Gong, Huang, Lorent, Dolan, Maraia, Pack: "Mutation of RNA Pol III subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and disrupts zebrafish digestive development." in: PLoS biology, Vol. 5, Issue 11, pp. e312, (2007) (PubMed).

  • Target
    POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
    Andere Bezeichnung
    POLR3B (POLR3B Produkte)
    Synonyme
    RGD1565311 antikoerper, C128 antikoerper, HLD8 antikoerper, RPC2 antikoerper, 2700078H01Rik antikoerper, A330032P03Rik antikoerper, C85372 antikoerper, RNA polymerase III subunit B antikoerper, polymerase (RNA) III (DNA directed) polypeptide B antikoerper, Polr3b antikoerper, POLR3B antikoerper
    Hintergrund
    POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
    Alias Symbols: FLJ10388, RPC2, C128, HLD8
    Protein Interaction Partner: SUMO2, UBC, POLR3H, TSR1, POLR1D, CRCP, POLR3A, POLR1C, POLR2H, POLR3D, RPAP2, RPAP1, GPN1, RAE1,
    Protein Size: 1133
    Molekulargewicht
    128 kDa
    Gen-ID
    55703
    NCBI Accession
    NM_018082, NP_060552
    UniProt
    Q9NW08
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