NEK11 Antikörper (Middle Region)

Produktnummer ABIN2783561

Produktdetails anti-NEK11 Antikörper

Target: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KEIRNEGSQP AYRTNQQDSD IEALARCLEN VLGCTSLDTK TITTMAEDMS

Homologie: Cow: 77%, Horse: 100%, Human: 100%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against NEK11. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NEK11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 645 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NEK11

Target: NEK11 (NIMA (Never In Mitosis Gene A)-Related Kinase 11 (NEK11))

Andere Bezeichnung: NEK11 (NEK11 Produkte)

Synonyme: nek11 antikoerper, MGC147549 antikoerper, 4932416N14Rik antikoerper, NIMA-related kinase 11 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 11 antikoerper, NIMA related kinase 11 antikoerper, nek11 antikoerper, Nek11 antikoerper, NEK11 antikoerper

Hintergrund: NEK11 is a member of the never in mitosis gene A family of kinases. NEK11 localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. It appears to play roles in DNA replication and response to genotoxic stress. NEK11 belongs to the NIMA family of kinases, which are involved in DNA replication and genotoxic stress responses (Noguchi et al., 2002 [PubMed 12154088]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2937 AB071996.1 1-2937
Alias Symbols: FLJ23495
Protein Interaction Partner: MYC, HSP90AA1, APP, NEK11, NEK2,
Protein Size: 645

Molekulargewicht: 74 kDa

Gen-ID: 79858

NCBI Accession: NM_024800, NP_079076

UniProt: Q8NG66