CDYL Antikörper (N-Term)

Produktnummer ABIN2783639

Produktdetails anti-CDYL Antikörper

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDYL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: YIHDFNRRHT EKQKESTLTR TNRTSPNNAR KQISRSTNSN FSKTSPKALV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CDYL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human CDYL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 544 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CDYL Antikörper (ABIN2783639)

Li, Xia, Huang, Chen, Su, Li, Wang, Ding, Shao: "A strategy to rapidly identify the functional targets of microRNAs by combining bioinformatics and mRNA cytoplasmic/nucleic ratios in culture cells." in: FEBS letters, Vol. 584, Issue 14, pp. 3198-202, (2010) (PubMed).

Details zu CDYL

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Andere Bezeichnung: CDYL (CDYL Produkte)

Synonyme: AI325931 antikoerper, CDYL1 antikoerper, chromodomain Y like antikoerper, chromodomain protein, Y chromosome-like antikoerper, chromodomain Y-like antikoerper, CDYL antikoerper, Cdyl antikoerper

Hintergrund: CDYL acts as repressor of transcription. CDYL has histone acetyltransferase activity, with a preference for histone H4.Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Alias Symbols: CDYL1, DKFZP586C1622, MGC131936
Protein Interaction Partner: UBC, HECW2, HDAC2, HDAC1, MIER1, MIER2, EHMT2, RBBP4, MYC, SUZ12, EZH2, CTBP1, WIZ, ZNF644, SETDB1, SMARCB1, SMARCA4, REST, HIST1H3A, HTRA1,
Protein Size: 544

Molekulargewicht: 60 kDa

Gen-ID: 9425

NCBI Accession: NM_004824, NP_004815

UniProt: Q9Y232