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SMPD3 Antikörper (Middle Region)

SMPD3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783713
  • Target Alle SMPD3 Antikörper anzeigen
    SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
    Bindungsspezifität
    • 14
    • 7
    • 5
    • 4
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 25
    • 2
    • 1
    Kaninchen
    Klonalität
    • 28
    Polyklonal
    Konjugat
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser SMPD3 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 17
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    RPPEADDPVP GGQARNGAGG GPRGQTPNHN QQDGDSGSLG SPSASRESLV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SMPD3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SMPD3
    Top Product
    Discover our top product SMPD3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 655 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tani, Hannun: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).

  • Target
    SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
    Andere Bezeichnung
    SMPD3 (SMPD3 Produkte)
    Synonyme
    4631433G07Rik antikoerper, AI427456 antikoerper, AW537966 antikoerper, fro antikoerper, nSMase2 antikoerper, cca1 antikoerper, NSMASE2 antikoerper, sphingomyelin phosphodiesterase 3 antikoerper, sphingomyelin phosphodiesterase 3, neutral antikoerper, SMPD3 antikoerper, Smpd3 antikoerper
    Hintergrund
    SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
    Alias Symbols: FLJ22593, MGC138443, NSMASE2
    Protein Size: 655
    Molekulargewicht
    71 kDa
    Gen-ID
    55512
    NCBI Accession
    NM_018667, NP_061137
    UniProt
    Q9NY59
    Pathways
    Hormone Transport
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