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SULF2 Antikörper (C-Term)

SULF2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783715
  • Target Alle SULF2 Antikörper anzeigen
    SULF2 (Sulfatase 2 (SULF2))
    Bindungsspezifität
    • 15
    • 9
    • 8
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 41
    • 18
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein
    Wirt
    • 53
    • 3
    • 1
    Kaninchen
    Klonalität
    • 54
    • 3
    Polyklonal
    Konjugat
    • 17
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SULF2 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 25
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    DVLNQLHVQL MELRSCKGYK QCNPRTRNMD LGLKDGGSYE QYRQFQRRKW
    Homologie
    Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SULF2. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human SULF2
    Top Product
    Discover our top product SULF2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 870 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Uchimura, Morimoto-Tomita, Bistrup, Li, Lyon, Gallagher, Werb, Rosen: "HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1." in: BMC biochemistry, Vol. 7, pp. 2, (2006) (PubMed).

  • Target
    SULF2 (Sulfatase 2 (SULF2))
    Andere Bezeichnung
    SULF2 (SULF2 Produkte)
    Synonyme
    Sulf1 antikoerper, zgc:55612 antikoerper, SULF2 antikoerper, si:dkeyp-84g9.1 antikoerper, wu:fb48e04 antikoerper, HSULF-2 antikoerper, xtsulf2 antikoerper, 2010004N24Rik antikoerper, AU020235 antikoerper, MSulf-2 antikoerper, mKIAA1247 antikoerper, sulfatase 2a antikoerper, sulfatase 2 antikoerper, extracellular sulfatase Sulf-2 antikoerper, sulfatase 2b antikoerper, sulfatase 2 S homeolog antikoerper, sulf2a antikoerper, SULF2 antikoerper, LOC100540921 antikoerper, sulf2 antikoerper, sulf2b antikoerper, sulf2.S antikoerper, Sulf2 antikoerper
    Hintergrund
    Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules.Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM].
    Alias Symbols: DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
    Protein Interaction Partner: MYC, UBC,
    Protein Size: 870
    Molekulargewicht
    98 kDa
    Gen-ID
    55959
    NCBI Accession
    NM_018837, NP_061325
    UniProt
    Q8IWU5
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