PCDHA5 Antikörper (N-Term)
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- Target Alle PCDHA5 Antikörper anzeigen
- PCDHA5 (Protocadherin alpha 5 (PCDHA5))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PCDHA5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VYSRRGSLGS RLLLLWLLLA YWKAGSGQLH YSIPEEAKHG TFVGRIAQDL
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PCDHA5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHA5
- Top Product
- Discover our top product PCDHA5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 936 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PCDHA5 (Protocadherin alpha 5 (PCDHA5))
- Andere Bezeichnung
- PCDHA5 (PCDHA5 Produkte)
- Synonyme
- CNR6 antikoerper, CNRN6 antikoerper, CNRS6 antikoerper, CRNR6 antikoerper, PCDH-ALPHA5 antikoerper, Cnr6 antikoerper, Crnr6 antikoerper, rCNRv05 antikoerper, PCDHA5 antikoerper, Pcdha5 antikoerper, protocadherin alpha 5 antikoerper, protocadherin alpha-5 antikoerper, PCDHA5 antikoerper, Pcdha5 antikoerper, LOC100738784 antikoerper, LOC100847156 antikoerper, LOC100713870 antikoerper, LOC100629824 antikoerper
- Hintergrund
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The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Alias Symbols: CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Protein Size: 936 - Molekulargewicht
- 99 kDa
- Gen-ID
- 56143
- NCBI Accession
- NM_018908, NP_061731
- UniProt
- Q9Y5H7
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