UGT2B4 Antikörper (N-Term)

Produktnummer ABIN2783820

Produktdetails anti-UGT2B4 Antikörper

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT2B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NIKTILDELV QRGHEVTVLA SSASISFDPN SPSTLKFEVY PVSLTKTEFE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UGT2B4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UGT2B4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 528 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UGT2B4

Target: UGT2B4 (UDP Glucuronosyltransferase 2 Family, Polypeptide B4 (UGT2B4))

Andere Bezeichnung: UGT2B4 (UGT2B4 Produkte)

Synonyme: HLUG25 antikoerper, UDPGTH1 antikoerper, UGT2B11 antikoerper, UDPGT2B4 antikoerper, UGT2B17 antikoerper, UGT2B28 antikoerper, UDP glucuronosyltransferase family 2 member B4 antikoerper, UDP-glucuronosyltransferase 2B4 antikoerper, UGT2B4 antikoerper, LOC615303 antikoerper, LOC100066359 antikoerper

Hintergrund: UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
Alias Symbols: UGT2B11, HLUG25, UDPGTH1, UDPGT2B4
Protein Interaction Partner: STAT5A,
Protein Size: 528

Molekulargewicht: 60 kDa

Gen-ID: 7363

NCBI Accession: NM_021139, NP_066962

UniProt: P06133

Pathways: Steroid Hormone Biosynthesis