ZP4 Antikörper (N-Term)
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- Target Alle ZP4 Antikörper anzeigen
- ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZP4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MWLLRCVLLC VSLSLAVSGQ HKPEAPDYSS VLHCGPWSFQ FAVNLNQEAT
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ZP4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZP4
- Top Product
- Discover our top product ZP4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 540 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
- Andere Bezeichnung
- ZP4 (ZP4 Produkte)
- Synonyme
- ZPB antikoerper, xlZPB antikoerper, lzpb-a antikoerper, MGC154827 antikoerper, zbp antikoerper, zp1 antikoerper, ZBP antikoerper, TAC4 antikoerper, MGC154888 antikoerper, ZP1 antikoerper, Zp-4 antikoerper, ZP3-ALPHA antikoerper, ZP antikoerper, Zp-X antikoerper, zona pellucida glycoprotein 4 S homeolog antikoerper, zona pellucida glycoprotein 4 antikoerper, zona pellucida glycoprotein 4 L homeolog antikoerper, zp4.S antikoerper, zp4 antikoerper, ZP4 antikoerper, zp4.L antikoerper, Zp4 antikoerper
- Hintergrund
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The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ZBP, ZP1, ZPB, Zp-4
Protein Interaction Partner: FURIN,
Protein Size: 540 - Molekulargewicht
- 49 kDa
- Gen-ID
- 57829
- NCBI Accession
- NM_021186, NP_067009
- UniProt
- Q12836
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