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ZP4 Antikörper (N-Term)

ZP4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783828
  • Target Alle ZP4 Antikörper anzeigen
    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 34
    • 3
    • 3
    • 1
    Human
    Wirt
    • 34
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ZP4 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 20
    • 15
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MWLLRCVLLC VSLSLAVSGQ HKPEAPDYSS VLHCGPWSFQ FAVNLNQEAT
    Homologie
    Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against ZP4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human ZP4
    Top Product
    Discover our top product ZP4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 540 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))
    Andere Bezeichnung
    ZP4 (ZP4 Produkte)
    Synonyme
    ZPB antikoerper, xlZPB antikoerper, lzpb-a antikoerper, MGC154827 antikoerper, zbp antikoerper, zp1 antikoerper, ZBP antikoerper, TAC4 antikoerper, MGC154888 antikoerper, ZP1 antikoerper, Zp-4 antikoerper, ZP3-ALPHA antikoerper, ZP antikoerper, Zp-X antikoerper, zona pellucida glycoprotein 4 S homeolog antikoerper, zona pellucida glycoprotein 4 antikoerper, zona pellucida glycoprotein 4 L homeolog antikoerper, zp4.S antikoerper, zp4 antikoerper, ZP4 antikoerper, zp4.L antikoerper, Zp4 antikoerper
    Hintergrund
    The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix.The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ZBP, ZP1, ZPB, Zp-4
    Protein Interaction Partner: FURIN,
    Protein Size: 540
    Molekulargewicht
    49 kDa
    Gen-ID
    57829
    NCBI Accession
    NM_021186, NP_067009
    UniProt
    Q12836
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