RHBDF1 Antikörper (N-Term)
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- Target Alle RHBDF1 Antikörper anzeigen
- RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RHBDF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RHBDF1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RHBDF1
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 855 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RHBDF1 (Rhomboid 5 Homolog 1 (RHBDF1))
- Andere Bezeichnung
- RHBDF1 (RHBDF1 Produkte)
- Synonyme
- zgc:91984 antikoerper, C16orf8 antikoerper, Dist1 antikoerper, EGFR-RS antikoerper, gene-89 antikoerper, gene-90 antikoerper, hDist1 antikoerper, C16ORF8 antikoerper, Dist antikoerper, Egfr-rs antikoerper, mKIAA4242 antikoerper, rhomboid 5 homolog 1 antikoerper, rhomboid 5 homolog 1a (Drosophila) antikoerper, RHBDF1 antikoerper, rhbdf1 antikoerper, rhbdf1a antikoerper, Rhbdf1 antikoerper
- Hintergrund
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RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
Alias Symbols: C16orf8, Dist1, EGFR-RS, FLJ2235, FLJ22357, gene -89, gene -90, hDist1, gene-89, gene-90
Protein Interaction Partner: UBC, TGFA,
Protein Size: 855 - Molekulargewicht
- 97 kDa
- Gen-ID
- 64285
- NCBI Accession
- NM_022450, NP_071895
- UniProt
- Q96CC6
- Pathways
- EGFR Signaling Pathway, Growth Factor Binding
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