NDST4 Antikörper (N-Term)

Produktnummer ABIN2783875

Produktdetails anti-NDST4 Antikörper

Target: NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Pferd, Kaninchen, Ratte, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDST4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EDWTIFQYNH STYQPVLLTE LQTEKSLSSL SSKTLFATVI QDLGLHDGIQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against NDST4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NDST4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 872 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NDST4

Target: NDST4 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 4 (NDST4))

Andere Bezeichnung: NDST4 (NDST4 Produkte)

Synonyme: NDST-4 antikoerper, NHSST4 antikoerper, 4930439H17Rik antikoerper, N-deacetylase and N-sulfotransferase 4 antikoerper, N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4 antikoerper, NDST4 antikoerper, Ndst4 antikoerper

Hintergrund: NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.
Alias Symbols: NDST-4, NHSST4
Protein Size: 872

Molekulargewicht: 101 kDa

Gen-ID: 64579

NCBI Accession: NM_022569, NP_072091

UniProt: Q9H3R1

Pathways: Glycosaminoglycan Metabolic Process