WNT3 Antikörper (Middle Region)
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- Target Alle WNT3 Antikörper anzeigen
- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WNT3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SHHKGPPGEG WKWGGCSEDA DFGVLVSREF ADARENRPDA RSAMNKHNNE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against WNT3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human WNT3
- Top Product
- Discover our top product WNT3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 355 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))
- Andere Bezeichnung
- WNT3 (WNT3 Produkte)
- Synonyme
- INT4 antikoerper, Ci-Wnt3 antikoerper, WNT3 antikoerper, int4 antikoerper, Xwnt3 antikoerper, wnt-3 antikoerper, wnt3l antikoerper, Xwnt-3 antikoerper, wnt3 antikoerper, Int-4 antikoerper, Wnt-3 antikoerper, wnt3-A antikoerper, Wnt family member 3 antikoerper, wingless-type MMTV integration site family, member 3 antikoerper, proto-oncogene Wnt-3 antikoerper, wingless-type MMTV integration site family member 3 antikoerper, Wnt family member 3A antikoerper, wingless-type MMTV integration site family member 3 L homeolog antikoerper, WNT3 antikoerper, Wnt3 antikoerper, wnt3 antikoerper, LOC468297 antikoerper, WNT3A antikoerper, wnt3.L antikoerper
- Hintergrund
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Alias Symbols: INT4, MGC131950, MGC138321, MGC138323
Protein Interaction Partner: FZD1,
Protein Size: 355 - Molekulargewicht
- 37 kDa
- Gen-ID
- 7473
- NCBI Accession
- NM_030753, NP_110380
- UniProt
- P56703
- Pathways
- WNT Signalweg, Regulation of Cell Size
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