BSCL2 Antikörper (C-Term)

Produktnummer ABIN2784048

Produktdetails anti-BSCL2 Antikörper

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BSCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QEESTPQSDV TEDGESPEDP SGTEGQLSEE EKPDQQPLSG EEELEPEAS

Homologie: Cow: 86%, Dog: 86%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BSCL2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BSCL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 462 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BSCL2

Target: BSCL2 (Berardinelli-Seip Congenital Lipodystrophy 2 (Seipin) (BSCL2))

Andere Bezeichnung: BSCL2 (BSCL2 Produkte)

Synonyme: GNG3LG antikoerper, HMN5 antikoerper, SPG17 antikoerper, 2900097C17Rik antikoerper, AI046355 antikoerper, Gng3lg antikoerper, BSCL2, seipin lipid droplet biogenesis associated antikoerper, Berardinelli-Seip congenital lipodystrophy 2 (seipin) antikoerper, BSCL2 antikoerper, Bscl2 antikoerper

Hintergrund: This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: GNG3LG, HMN5, MGC4694, SPG17
Protein Interaction Partner: SMLR1, SMIM3, PLEKHF2, TMEM19, NSG1, SUMO2, SUMO3, Hoxa1, UBC, CANX, USE1,
Protein Size: 462

Molekulargewicht: 51 kDa

Gen-ID: 26580

NCBI Accession: NM_001122955, NP_001116427

UniProt: Q96G97