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DISP1 Antikörper (Middle Region)

DISP1 Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784069
  • Target Alle DISP1 Antikörper anzeigen
    DISP1 (Dispatched Homolog 1 (DISP1))
    Bindungsspezifität
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schwein
    Wirt
    • 5
    • 1
    Kaninchen
    Klonalität
    • 6
    Polyklonal
    Konjugat
    • 6
    Dieser DISP1 Antikörper ist unkonjugiert
    Applikation
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    FVLCDVWNYT KFDKPHAETS ETVSITLQHA ALSMFVTSFT TAAAFYANYV
    Homologie
    Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 100%, Rat: 86%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DISP1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human DISP1
    Top Product
    Discover our top product DISP1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1524 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DISP1 (Dispatched Homolog 1 (DISP1))
    Andere Bezeichnung
    DISP1 (DISP1 Produkte)
    Synonyme
    DISP1 antikoerper, DISPA antikoerper, 1190008H24Rik antikoerper, DispA antikoerper, con antikoerper, zgc:111866 antikoerper, dispatched antikoerper, dispatched RND transporter family member 1 antikoerper, dispatched homolog 1 (Drosophila) antikoerper, CpipJ_CPIJ008642 antikoerper, DISP1 antikoerper, Disp1 antikoerper, disp1 antikoerper
    Hintergrund
    DISP1 functions in hedgehog (Hh) signaling. Regulates the release and extracellular accumulation of cholesterol-modified hedgehog proteins and is hence required for effective production of the Hh signal.The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
    Alias Symbols: DISPA, DKFZP434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
    Protein Interaction Partner: LAPTM5, UBC,
    Protein Size: 1524
    Molekulargewicht
    171 kDa
    Gen-ID
    84976
    NCBI Accession
    NM_032890, NP_116279
    UniProt
    Q96F81
    Pathways
    Hedgehog Signalweg
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