PCDH15 Antikörper (N-Term)

Produktnummer ABIN2784074

Produktdetails anti-PCDH15 Antikörper

Target: PCDH15 (Protocadherin-15 (PCDH15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDH15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HSIVVQVQCI NKKVGTIIYH EVRIVVRDRN DNSPTFKHES YYATVNELTP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDH15. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PCDH15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 719 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PCDH15

Target: PCDH15 (Protocadherin-15 (PCDH15))

Andere Bezeichnung: PCDH15 (PCDH15 Produkte)

Synonyme: CDHR15 antikoerper, DFNB23 antikoerper, USH1F antikoerper, BB078305 antikoerper, ENSMUSG00000046980 antikoerper, Gm9815 antikoerper, Ush1f antikoerper, av antikoerper, nmf19 antikoerper, protocadherin-15 antikoerper, protocadherin related 15 antikoerper, protocadherin-15 antikoerper, protocadherin 15 antikoerper, PCDH15 antikoerper, CpipJ_CPIJ005081 antikoerper, Pcdh15 antikoerper

Hintergrund: PCDH15 is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. PCDH15 consists of a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain and a unique cytoplasmic domain. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene have been associated with hearing loss, which is consistent with its location at the Usher syndrome type 1F (USH1F) critical region on chromosome 10.
Alias Symbols: RP11-449J3.2, DFNB23, DKFZp667A1711, USH1F, CDHR15
Protein Interaction Partner: Dlg4,
Protein Size: 719

Molekulargewicht: 80 kDa

Gen-ID: 65217

NCBI Accession: NM_001142763

UniProt: A2A3E5

Pathways: Sensory Perception of Sound