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SIGLEC10 Antikörper (Middle Region)

SIGLEC10 Reaktivität: Human, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784077
  • Target Alle SIGLEC10 Antikörper anzeigen
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    Bindungsspezifität
    • 8
    • 7
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 45
    • 1
    • 1
    Human, Hund
    Wirt
    • 33
    • 12
    • 1
    Kaninchen
    Klonalität
    • 34
    • 12
    Polyklonal
    Konjugat
    • 16
    • 7
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIGLEC10 Antikörper ist unkonjugiert
    Applikation
    • 28
    • 26
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    CHVDFSRKGV SAQRTVRLRV AYAPRDLVIS ISRDNTPALE PQPQGNVPYL
    Homologie
    Dog: 79%, Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SIGLEC10. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC10
    Top Product
    Discover our top product SIGLEC10 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 697 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Szafranski, Schindler, Taudien, Hiller, Huse, Jahn, Schreiber, Backofen, Platzer: "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns." in: Genome biology, Vol. 8, Issue 8, pp. R154, (2008) (PubMed).

  • Target
    SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
    Andere Bezeichnung
    SIGLEC10 (SIGLEC10 Produkte)
    Synonyme
    PRO940 antikoerper, SIGLEC-10 antikoerper, SLG2 antikoerper, Siglecg antikoerper, SIGLEC10 antikoerper, slg2 antikoerper, pro940 antikoerper, siglec-10 antikoerper, sialic acid binding Ig like lectin 10 antikoerper, sialic acid binding Ig-like lectin 10 antikoerper, sialic acid-binding Ig-like lectin 10 antikoerper, SIGLEC10 antikoerper, Siglec10 antikoerper, LOC484343 antikoerper, LOC100066644 antikoerper, siglec10 antikoerper, LOC100513863 antikoerper, LOC100340374 antikoerper
    Hintergrund
    SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-653 AC008750.9 90495-91147 c 654-760 DA387605.1 391-497 761-2959 AF301007.1 262-2460 2960-3794 AY358337.1 1930-2764
    Alias Symbols: MGC126774, PRO940, SIGLEC-10, SLG2
    Protein Interaction Partner: FLNA, PTPN6,
    Protein Size: 697
    Molekulargewicht
    76 kDa
    Gen-ID
    89790
    NCBI Accession
    NM_033130, NP_149121
    UniProt
    Q96LC7
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