COLEC12 Antikörper (Middle Region)

Produktnummer ABIN311281

Produktdetails anti-COLEC12 Antikörper

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COLEC12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AGERGPIGPA GPPGERGGKG SKGSQGPKGS RGSPGKPGPQ GPSGDPGPPG

Homologie: Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against COLEC12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COLEC12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 742 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Andere Bezeichnung: COLEC12 (COLEC12 Produkte)

Hintergrund: COLEC12 is a member of the C-lectin family,!!proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.
Alias Symbols: CLP1, NSR2, SCARA4, SRCL
Protein Interaction Partner: APP, EXOC1,
Protein Size: 742

Molekulargewicht: 81 kDa

Gen-ID: 81035

NCBI Accession: NM_130386, NP_569057

UniProt: Q5KU26

Pathways: Activation of Innate immune Response