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SSX4B Antikörper (Middle Region)

SSX4B Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784178
  • Target Alle SSX4B Antikörper anzeigen
    SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
    Bindungsspezifität
    Middle Region
    Reaktivität
    Human
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser SSX4B Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB)
    Sequenz
    MRSKRAADFH GNDFGNDRNH RNQVERPQMT FGSLQRIFPK IMPKKPAEEE
    Homologie
    Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SSX4B. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SSX4B
    Top Product
    Discover our top product SSX4B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 188 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SSX4B (Synovial Sarcoma, X Breakpoint 4B (SSX4B))
    Andere Bezeichnung
    SSX4B (SSX4B Produkte)
    Synonyme
    CT5.4 antikoerper, SSX family member 4B antikoerper, SSX4B antikoerper
    Hintergrund
    The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: SSX4, CT5.4
    Protein Interaction Partner: HIF1A,
    Protein Size: 188
    Molekulargewicht
    22 kDa
    Gen-ID
    548313
    NCBI Accession
    NM_001034832, NP_001030004
    UniProt
    O60224
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