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FIP200 Antikörper (C-Term)

RB1CC1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784196
  • Target Alle FIP200 (RB1CC1) Antikörper anzeigen
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Bindungsspezifität
    • 15
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 28
    • 21
    • 17
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 54
    • 2
    Kaninchen
    Klonalität
    • 54
    • 2
    Polyklonal
    Konjugat
    • 20
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FIP200 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 29
    • 13
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    SGASRRPWVL GKVMEKEYCQ AKKAQNRFKV PLGTKFYRVK AVSWNKKV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against RB1CC1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human RB1CC1
    Top Product
    Discover our top product RB1CC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1591 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FIP200 (RB1CC1) (RB1-Inducible Coiled-Coil 1 (RB1CC1))
    Andere Bezeichnung
    RB1CC1 (RB1CC1 Produkte)
    Synonyme
    DKFZp459E2330 antikoerper, CC1 antikoerper, FIP200 antikoerper, 2900055E04Rik antikoerper, 5930404L04Rik antikoerper, Cc1 antikoerper, LaXp180 antikoerper, RB1 inducible coiled-coil 1 antikoerper, RB1 inducible coiled-coil 1 L homeolog antikoerper, RB1-inducible coiled-coil 1 antikoerper, RB1CC1 antikoerper, rb1cc1.L antikoerper, rb1cc1 antikoerper, Rb1cc1 antikoerper
    Hintergrund
    RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
    Alias Symbols: CC1, DRAGOU14, FIP200
    Protein Interaction Partner: ATG16L1, SESN2, ATG5, UBC, EXOC1, DYRK2, PINK1, CALCOCO2, RFWD2, CTNNB1, GABARAPL1, GABARAP, VHL, RNF111, SMARCB1, SKIL, SKI, TBKBP1, TP53, ATG13, ULK2, SAFB2, ULK1, SAFB, RPA2, RPA1, PRKAB2, PRKAA2, HSBP1, MAP1LC3C, SMCR8, ATG101, YLPM1, TBK1, RBMX, PTK2
    Protein Size: 1591
    Molekulargewicht
    183 kDa
    Gen-ID
    9821
    NCBI Accession
    NM_001083617, NP_001077086
    UniProt
    Q8TDY2
    Pathways
    Regulation of Cell Size, Autophagie
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