SPRY4 Antikörper (Middle Region)
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- Target Alle SPRY4 Antikörper anzeigen
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SPRY4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LCYLPATGCV KLAQRGYDRL RRPGCRCKHT NSVICKAASG DAKTSRPDKP
- Homologie
- Cow: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SPRY4. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SPRY4
- Top Product
- Discover our top product SPRY4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 322 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
- Andere Bezeichnung
- SPRY4 (SPRY4 Produkte)
- Synonyme
- SPRY4 antikoerper, LOC100218545 antikoerper, HH17 antikoerper, A030006O18Rik antikoerper, sprouty4 antikoerper, sprouty RTK signaling antagonist 4 antikoerper, sprouty (Drosophila) homolog 4 antikoerper, sprouty homolog 4 (Drosophila) antikoerper, Spry4 antikoerper, SPRY4 antikoerper, spry4 antikoerper
- Hintergrund
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SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS, MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 [PubMed 12027893]).
Alias Symbols: -
Protein Interaction Partner: GRB2, SPRY2, SPRY4, TESK1, RAF1, CBL,
Protein Size: 322 - Molekulargewicht
- 35 kDa
- Gen-ID
- 81848
- NCBI Accession
- NM_030964, NP_112226
- UniProt
- Q9C004
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