DCP1B Antikörper (N-Term)

Produktnummer ABIN2784340

Produktdetails anti-DCP1B Antikörper

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCP1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLDPEPQHLS LTALFGKQDK ATCQETVEPP QTLHQQQQQQ QQQQEKLPIR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DCP1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DCP1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 617 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DCP1B

Target: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Andere Bezeichnung: DCP1B (DCP1B Produkte)

Hintergrund: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-844 AY146652.1 1-844 845-2079 BC015368.2 379-1613 2080-2105 AW204088.1 3-28 c
Alias Symbols: DCP1, hDcp1b
Protein Interaction Partner: EDC3, ZFP36, UBC, E2F7, DCP1A, EDC4, PPM1A, DDX6, DCP2, KANK2, PNRC1, BAG4, EXOSC6, XRN1, LSM8, UPF2, SMAD4, HSPA1L, USP4,
Protein Size: 617

Molekulargewicht: 68 kDa

Gen-ID: 196513

NCBI Accession: NM_152640, NP_689853

UniProt: Q8IZD4