GTF2A1L Antikörper (C-Term)

Produktnummer ABIN311360

Produktdetails anti-GTF2A1L Antikörper

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Pferd, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2A1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RVTDDDIGEI IQVDGSGDTS SNEEIGSTRD ADENEFLGNI DGGDLKVPEE

Homologie: Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GTF2A1L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GTF2A1L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 478 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GTF2A1L

Target: GTF2A1L (General Transcription Factor IIA, 1-Like (GTF2A1L))

Andere Bezeichnung: GTF2A1L (GTF2A1L Produkte)

Hintergrund: The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alias Symbols: ALF, MGC26254
Protein Interaction Partner: GAB1, NKX2-3, ZBTB3, TLX3, MAFF, RBFOX2, HMG20A, PAX9, SIX6, MAFG, HOXC11, HOXC9, HOXA5, TLX2, EMX2, EMX1, CEBPE, ATF4, ASCL3, GTF2A2, SUB1, ID3, CSNK2A2, CSNK2A1, TBP,
Protein Size: 478

Molekulargewicht: 52 kDa

Gen-ID: 11036

NCBI Accession: NM_006872, NP_006863

UniProt: Q9UNN4