WDFY3 Antikörper (C-Term)

Produktnummer ABIN2784358

Produktdetails anti-WDFY3 Antikörper

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Schwein, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDFY3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EKLADAVRFL GCFSDLRKIS AMNVFPSNTQ PFQRLLEEDV ISIESVSPTL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against WDFY3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human WDFY3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 795 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WDFY3 Antikörper (ABIN2784358)

Yao, Jia, Feathers, Lin, Khan, Klionsky, Ferguson, Zacks: "Autophagy-mediated catabolism of visual transduction proteins prevents retinal degeneration." in: Autophagy, Vol. 12, Issue 12, pp. 2439-2450, (2016) (PubMed).

Details zu WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Andere Bezeichnung: WDFY3 (WDFY3 Produkte)

Synonyme: ALFY antikoerper, ZFYVE25 antikoerper, 2610509D04Rik antikoerper, AW319683 antikoerper, B930017C24 antikoerper, BWF1 antikoerper, Bchs antikoerper, D5Ertd66e antikoerper, Ggtb3 antikoerper, mKIAA0993 antikoerper, WDFY family member 4 antikoerper, WD repeat and FYVE domain containing 3 antikoerper, WD repeat and FYVE domain-containing protein 3 antikoerper, WDFY4 antikoerper, WDFY3 antikoerper, MGYG_03998 antikoerper, Wdfy3 antikoerper

Hintergrund: WDFY3 is a protein which contains WD repeats and an FYVE domain. WDFY3 might target cytosolic protein aggregates for autophagic degradation.This gene encodes a protein which contains WD repeats and an FYVE domain. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: ALFY, KIAA0993, MGC16461, ZFYVE25
Protein Interaction Partner: CEP76, TRIM39, ZBTB44, PRMT6, SUV39H1, PRMT1, SQSTM1, TRAF6, BAG3, EEF2K, ATG16L1, ATG5, ATG12, MAP1LC3A, UBC,
Protein Size: 795

Molekulargewicht: 90 kDa

Gen-ID: 23001

NCBI Accession: NM_178583, NP_848698

UniProt: Q8IZQ1