Frataxin Antikörper (C-Term)
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- Target Alle Frataxin (FXN) Antikörper anzeigen
- Frataxin (FXN)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Frataxin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EFFEDLADKP YTLKDYDVSF GDGVLTIKLG GDLGTYVINK QTPNKQIWLS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Fxn. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Rat
- Top Product
- Discover our top product FXN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 208 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Frataxin (FXN)
- Andere Bezeichnung
- Fxn (FXN Produkte)
- Synonyme
- zgc:158218 antikoerper, LOC100284365 antikoerper, BcDNA:AT09528 antikoerper, CG8971 antikoerper, DFH antikoerper, Dfh antikoerper, Dmel\\CG8971 antikoerper, X25 antikoerper, dfh antikoerper, CyaY antikoerper, FA antikoerper, FARR antikoerper, FRDA antikoerper, RGD1565754 antikoerper, Frda antikoerper, frataxin antikoerper, fxn antikoerper, LOC100284365 antikoerper, TVAG_182150 antikoerper, fh antikoerper, FTX1 antikoerper, FXN antikoerper, Fxn antikoerper
- Hintergrund
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Fxn promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. It may play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. It may be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization. Fxn modulates the RNA-binding activity of ACO1.
Alias Symbols: RGD1565754, Fxn
Protein Size: 208 - Molekulargewicht
- 23 kDa
- Gen-ID
- 499335
- NCBI Accession
- NM_001191952, XP_001078791
- UniProt
- D3ZYW7
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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