PHF6 Antikörper (N-Term)

Produktnummer ABIN2784476

Produktdetails anti-PHF6 Antikörper

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Hund, Rind (Kuh), Pferd, Ratte, Kaninchen, Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VGQNHSEDGA PALLTTAPPP GLQPGAGGTP GGPGGGGAPP RYATLEHPFH

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHF6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 365 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Andere Bezeichnung: PHF6 (PHF6 Produkte)

Synonyme: zgc:55403 antikoerper, wu:fa22g03 antikoerper, BFLS antikoerper, BORJ antikoerper, CENP-31 antikoerper, 2700007B13Rik antikoerper, 4931428F02Rik antikoerper, mKIAA1823 antikoerper, PHD finger protein 6 antikoerper, PHD finger protein 6 L homeolog antikoerper, phf6 antikoerper, phf6.L antikoerper, PHF6 antikoerper, Phf6 antikoerper

Hintergrund: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears.This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: BORJ, MGC14797, BFLS, CENP-31
Protein Interaction Partner: UBC, SUMO1, NEDD8, BMI1, HECW2, CAND1, CUL3, HDGF,
Protein Size: 365

Molekulargewicht: 41 kDa

Gen-ID: 84295

NCBI Accession: NM_032458, NP_115834

UniProt: Q8IWS0