PHC2 Antikörper (N-Term)

Produktnummer ABIN2784482

Produktdetails anti-PHC2 Antikörper

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GGSGRPTGPQ ISVYSGIPDR QTVQVIQQAL HRQPSTAAQY LQQMYAAQQQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PHC2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 858 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHC2

Target: PHC2 (PhC2) (Polyhomeotic Homolog 2 (Drosophila) (PhC2))

Andere Bezeichnung: PHC2 (PhC2 Produkte)

Synonyme: EDR2 antikoerper, HPH2 antikoerper, PH2 antikoerper, A3galt2 antikoerper, AA415044 antikoerper, D130050K19Rik antikoerper, D4Ertd810e antikoerper, Edr2 antikoerper, Mph2 antikoerper, p36 antikoerper, cb218 antikoerper, edr2 antikoerper, id:ibd2745 antikoerper, id:ibd5044 antikoerper, ph2 antikoerper, ph2[a] antikoerper, ph2[b] antikoerper, ph2alpha antikoerper, ph2beta antikoerper, phc2 antikoerper, wu:fb98c05 antikoerper, wu:fc96f07 antikoerper, zgc:100775 antikoerper, zgc:123102 antikoerper, polyhomeotic homolog 2 L homeolog antikoerper, polyhomeotic homolog 2 antikoerper, polyhomeotic-like 2 (Drosophila) antikoerper, polyhomeotic homolog 2a (Drosophila) antikoerper, phc2.L antikoerper, PHC2 antikoerper, Phc2 antikoerper, phc2a antikoerper

Hintergrund: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EDR2, HPH2, MGC163502, PH2
Protein Interaction Partner: FAM74A4, FAM74A1, FAM13C, FAM124A, MAGEB6, ZMAT2, ZNF417, MAB21L3, SSX2IP, TRIM41, ZGPAT, L3MBTL3, PCGF5, SPATC1L, FAM161A, ENKD1, KBTBD7, SYT16, THAP7, AEN, CARD9, CBX8, C1orf109, SFMBT1, PRPF31, PPP1R16B, KAT5, PCGF3, RWDD2B, ZBTB24, MORF4L2, RBM39, AP1
Protein Size: 858

Molekulargewicht: 91 kDa

Gen-ID: 1912

NCBI Accession: NM_198040, NP_932157

UniProt: Q8IXK0