HNF1A Antikörper (N-Term)

Produktnummer ABIN2784536

Produktdetails anti-HNF1A Antikörper

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: HAGQGGLIEE PTGDELPTKK GRRNRFKWGP ASQQILFQAY ERQKNPSKEE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 631 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HNF1A Antikörper (ABIN2784536)

Scheving, Zhang, Garcia, Wang, Stevenson, Threadgill, Russell: "Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 306, Issue 5, pp. G370-81, (2014) (PubMed).

Details zu HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Andere Bezeichnung: HNF1A (HNF1A Produkte)

Hintergrund: HNF1A is required for the expression of several liver specific genes. HNF1A binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Alias Symbols: HNF1, LFB1, MODY3, TCF1, TCF-1, HNF-1A, IDDM20
Protein Interaction Partner: RNF14, RYR3, RAC3, PCBD1, HIST2H2AB, RPSAP15, SNX14, CBX3, YWHAZ, YWHAG, YWHAE, YWHAB, VIM, VCP, HNF1A, SRSF7, RANBP1, PEBP1, LDHA, IGFBP7, HMGB1, ANXA2, ACTB, SIRT1, BCL6, EP300, CREBBP, GATA5, HNF1B, KAT2B, CDX2, HNF4A, TLE1, SRC, FOS, POU2F1, BCR, CEBP
Protein Size: 631

Molekulargewicht: 67 kDa

Gen-ID: 6927

NCBI Accession: NM_000545, NP_000536

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis