gamma 1 Adaptin Antikörper (C-Term)

Produktnummer ABIN2784689

Produktdetails anti-gamma 1 Adaptin Antikörper

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser gamma 1 Adaptin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DHMRSALLER MPVMEKVTTN GPTEIVQTNG ETEPAPLETK PPPSGPQPTS

Homologie: Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AP1G1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP1G1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 822 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu gamma 1 Adaptin

Target: gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))

Andere Bezeichnung: AP1G1 (AP1G1 Produkte)

Hintergrund: Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family.Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADTG, CLAPG1, MGC18255
Protein Interaction Partner: UBL7, AP1S2, UBC, EGFR, GPRASP2, PASK, ASB10, PRRC1, OSBPL11, NPM3, TRIP10, KIF13A, ZNF512B, SYNRG, RABEP1, AP1M1, MAP1A, AP1S1, AP2M1, AP1B1, CLINT1, CLTC, gag, JUN, AP1AR, RABGEF1, AFTPH, DNER, AP1M2, AP1G1, SYP, SPTB, ARF1, AP2S1, NECAP2, NECAP1, RAB5A
Protein Size: 822

Molekulargewicht: 91 kDa

Gen-ID: 164

NCBI Accession: NM_001128, NP_001119

UniProt: O43747