DPH1 Antikörper (N-Term)

Produktnummer ABIN2784707

Produktdetails anti-DPH1 Antikörper

Target: DPH1 (DPH1 Homolog (DPH1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Kaninchen, Ratte, Hund, Meerschweinchen, Pferd, Rind (Kuh), Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NQIPPEILKN PQLQAAIRVL PSNYNFEIPK TIWRIQQAQA KKVALQMPEG

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DPH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DPH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 443 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DPH1

Target: DPH1 (DPH1 Homolog (DPH1))

Andere Bezeichnung: DPH1 (DPH1 Produkte)

Synonyme: DPH1 antikoerper, DPH1-OVCA2 antikoerper, dph1-ovca2 antikoerper, dph2l antikoerper, dph2l1 antikoerper, ovca1 antikoerper, DPH2L antikoerper, DPH2L1 antikoerper, OVCA1 antikoerper, zgc:110702 antikoerper, 2310011M22Rik antikoerper, 4930488F09Rik antikoerper, AW551873 antikoerper, Dph2l1 antikoerper, Ovca1 antikoerper, RGD1562694 antikoerper, diphthamide biosynthesis 1 antikoerper, diphthamide biosynthesis protein 1 antikoerper, diphthamide biosynthesis 1 L homeolog antikoerper, 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 antikoerper, DPH1 antikoerper, NCU08503 antikoerper, ATEG_01183 antikoerper, LELG_00973 antikoerper, HCAG_03806 antikoerper, AOR_1_728014 antikoerper, PTRG_05729 antikoerper, CTRG_01524 antikoerper, UREG_06411 antikoerper, BDBG_05574 antikoerper, MCYG_04396 antikoerper, PITG_12187 antikoerper, MGYG_02224 antikoerper, LOC100284663 antikoerper, dph1.L antikoerper, dph1 antikoerper, Dph1 antikoerper, dph-1 antikoerper

Hintergrund: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH1 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).
Alias Symbols: DPH2L, DPH2L1, FLJ33211, OVCA1
Protein Interaction Partner: UBC, TFCP2, MMS19, UBD, TP63, TP73, TP53, RBM8A, HSPA5,
Protein Size: 443

Molekulargewicht: 49 kDa

Gen-ID: 1801

NCBI Accession: NM_001383, NP_001374

UniProt: Q9BZG8