DBT Antikörper (N-Term)

Produktnummer ABIN2784728

Produktdetails anti-DBT Antikörper

Target: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DBT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NYVCFFGYPS FKYSHPHHFL KTTAALRGQV VQFKLSDIGE GIREVTVKEW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DBT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DBT

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 482 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DBT

Target: DBT (Dihydrolipoamide Branched Chain Transacylase E2 (DBT))

Andere Bezeichnung: DBT (DBT Produkte)

Synonyme: BCATE2 antikoerper, BCKAD-E2 antikoerper, BCKADE2 antikoerper, E2 antikoerper, E2B antikoerper, D3Wsu60e antikoerper, im:7147214 antikoerper, zgc:103768 antikoerper, E2b antikoerper, dihydrolipoamide branched chain transacylase E2 antikoerper, hypothetical protein antikoerper, dihydrolipoamide branched chain transacylase E2 L homeolog antikoerper, DBT antikoerper, dbt antikoerper, CpipJ_CPIJ006326 antikoerper, BDBG_05874 antikoerper, NAEGRDRAFT_78509 antikoerper, VDBG_04820 antikoerper, PGTG_17722 antikoerper, Dbt antikoerper, dbt.L antikoerper

Substanzklasse: Viral Protein

Hintergrund: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO2. It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BCATE2, E2, E2B, MGC9061
Protein Interaction Partner: HUWE1, UBC, PARK2, IFIT2, ABCC1, DLD, AGO4, AGO3, SRRM2, USP16, ADI1,
Protein Size: 482

Molekulargewicht: 46 kDa

Gen-ID: 1629

NCBI Accession: NM_001918, NP_001909

UniProt: P11182