Protein Tob1 (TOB1) (Middle Region) Antikörper
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- Target Alle Protein Tob1 (TOB1) Antikörper anzeigen
- Protein Tob1 (TOB1)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT
- Homologie
- Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TOB1
- Top Product
- Discover our top product TOB1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 345 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Protein Tob1 (TOB1)
- Andere Bezeichnung
- TOB1 (TOB1 Produkte)
- Synonyme
- Tob antikoerper, Trob antikoerper, APRO5 antikoerper, APRO6 antikoerper, PIG49 antikoerper, TOB antikoerper, TROB antikoerper, TROB1 antikoerper, tob1 antikoerper, tob1l antikoerper, wu:fb54d02 antikoerper, wu:fb98h12 antikoerper, wu:fd15f10 antikoerper, zgc:65837 antikoerper, transducer of ErbB-2.1 antikoerper, transducer of ERBB2, 1 antikoerper, transducer of ERBB2, 1a antikoerper, transducer of ERBB2, 1 S homeolog antikoerper, transducer of ERBB2, 1b antikoerper, Tob1 antikoerper, TOB1 antikoerper, tob1a antikoerper, tob1.S antikoerper, tob1b antikoerper
- Hintergrund
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This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
Protein Interaction Partner: CORO7, APP, DTL, CDC7, PABPC1, CHAF1A, PAN2, UBR5, ELAVL1, SMAD3, CTNNB1, UBC, SKP2, SCMH1, MARCKS, SETDB1, CNOT7, SMAD9, SMAD5, SMAD6, SMAD1, SMAD2, SMAD4, MAPK1, ERBB2, RPS6KA1, MAPK9,
Protein Size: 345 - Molekulargewicht
- 38 kDa
- Gen-ID
- 10140
- NCBI Accession
- NM_005749, NP_005740
- UniProt
- P50616
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