HSPH1 Antikörper (Middle Region)

Produktnummer ABIN2784830

Produktdetails anti-HSPH1 Antikörper

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EENEMSSEAD MECLNQRPPE NPDTDKNVQQ DNSEAGTQPQ VQTDAQQTSQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HSPH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSPH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 858 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSPH1 Antikörper (ABIN2784830)

Du, Rong, Hui, Peng, Jin, Li, Wang, Li: "Expression and function of HSP110 family in mouse testis after vasectomy." in: Asian journal of andrology, Vol. 19, Issue 3, pp. 355-361, (2016) (PubMed).

Details zu HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Andere Bezeichnung: HSPH1 (HSPH1 Produkte)

Hintergrund: HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. It inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alias Symbols: DKFZp686M05240, HSP105, HSP105A, HSP105B, KIAA0201, NY-CO-25
Protein Interaction Partner: HUWE1, UBC, SUMO2, SUMO3, HSPA8, MDM2, ILK, SET, PPM1G, PLOD2, HSPA4, DPYSL2, CTNNA1, PARVA, PUS7, SAMHD1, XPO7, FAF1, CARM1, SEC23A, PRMT3, FARSB, RANBP3, HIRIP3, HIST1H4A, USP11, SF1, UGP2, HECW2, FBXO6, TARDBP, CFTR, METTL21A, env, NOS2, HSP90AB1, HSP9
Protein Size: 858

Molekulargewicht: 97 kDa

Gen-ID: 10808

NCBI Accession: NM_006644, NP_006635

UniProt: Q92598