Dynamin 1-Like Antikörper (N-Term)

Produktnummer ABIN2784887

Produktdetails anti-Dynamin 1-Like Antikörper

Target: Dynamin 1-Like (DNM1L)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 736 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Dynamin 1-Like Antikörper (ABIN2784887)

Su, Chiu, Hung, Hong: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L (DNM1L Produkte)

Synonyme: DLP1 antikoerper, DRP1 antikoerper, DVLP antikoerper, DYMPLE antikoerper, EMPF antikoerper, HDYNIV antikoerper, 6330417M19Rik antikoerper, AI450666 antikoerper, Dlp1 antikoerper, Dnmlp1 antikoerper, Drp1 antikoerper, python antikoerper, Dnml1 antikoerper, dnm1l antikoerper, MGC53850 antikoerper, zgc:66163 antikoerper, DNM1L antikoerper, 18.m06247 antikoerper, CG3210 antikoerper, DRP antikoerper, Dmel\CG3210 antikoerper, Dnm1/Drp1 antikoerper, Drp antikoerper, Drp-1 antikoerper, drp-1 antikoerper, drp1 antikoerper, frat antikoerper, l(2)22Fc antikoerper, l(2)22Fd antikoerper, l(2)ND2 antikoerper, l(2)ND3 antikoerper, dynamin 1 like antikoerper, dynamin 1-like antikoerper, dynamin 1-like L homeolog antikoerper, dynamin-1-like antikoerper, dynamin-1-like protein antikoerper, dynamin-like protein antikoerper, Dynamin related protein 1 antikoerper, DNM1L antikoerper, Dnm1l antikoerper, dnm1l.L antikoerper, dnm1l antikoerper, LOC100369408 antikoerper, LOC411472 antikoerper, dyn1 antikoerper, cgd1_580 antikoerper, EHI_052740 antikoerper, PVX_092875 antikoerper, BBOV_II002980 antikoerper, Drp1 antikoerper

Hintergrund: The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
Alias Symbols: DLP1, DRP1, DVLP, DYMPLE, HDYNIV, VPS1, EMPF, DYNIV-11
Protein Interaction Partner: ZBTB24, UBC, SCG3, SH3GL1, RRM2, MAGEA3, MAGEA1, MARCH5, EGFR, VPS26A, SSB, CARS, ATP6V1C1, APEH, PSMG3, FAM129B, TBC1D15, CYHR1, ARFIP1, JMJD6, SEC24A, SOX2, DNM1L, MIEF2, MFF, PEX14, LRRK2, MIEF1, COPS5, GABRR1, MUL1, SUMO2, PARK2, PEX25, PEX11G, PEX11A
Protein Size: 736

Molekulargewicht: 82 kDa

Gen-ID: 10059

NCBI Accession: NM_012062, NP_036192

UniProt: O00429