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Dynamin 1-Like Antikörper (N-Term)

DNM1L Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784887
  • Target Alle Dynamin 1-Like (DNM1L) Antikörper anzeigen
    Dynamin 1-Like (DNM1L)
    Bindungsspezifität
    • 23
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 51
    • 44
    • 27
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 58
    • 8
    Kaninchen
    Klonalität
    • 58
    • 8
    Polyklonal
    Konjugat
    • 32
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dynamin 1-Like Antikörper ist unkonjugiert
    Applikation
    • 33
    • 28
    • 17
    • 13
    • 13
    • 12
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    IRQEIENETE RISGNNKGVS PEPIHLKIFS PNVVNLTLVD LPGMTKVPVG
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DNM1L. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DNM1L
    Top Product
    Discover our top product DNM1L Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 736 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Su, Chiu, Hung, Hong: "Beta-nodavirus B2 protein induces hydrogen peroxide production, leading to Drp1-recruited mitochondrial fragmentation and cell death via mitochondrial targeting." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 10, pp. 1457-70, (2014) (PubMed).

  • Target
    Dynamin 1-Like (DNM1L)
    Andere Bezeichnung
    DNM1L (DNM1L Produkte)
    Hintergrund
    The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated.
    Alias Symbols: DLP1, DRP1, DVLP, DYMPLE, HDYNIV, VPS1, EMPF, DYNIV-11
    Protein Interaction Partner: ZBTB24, UBC, SCG3, SH3GL1, RRM2, MAGEA3, MAGEA1, MARCH5, EGFR, VPS26A, SSB, CARS, ATP6V1C1, APEH, PSMG3, FAM129B, TBC1D15, CYHR1, ARFIP1, JMJD6, SEC24A, SOX2, DNM1L, MIEF2, MFF, PEX14, LRRK2, MIEF1, COPS5, GABRR1, MUL1, SUMO2, PARK2, PEX25, PEX11G, PEX11A
    Protein Size: 736
    Molekulargewicht
    82 kDa
    Gen-ID
    10059
    NCBI Accession
    NM_012062, NP_036192
    UniProt
    O00429
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