COPB1 Antikörper (Middle Region)

Produktnummer ABIN2784899

Produktdetails anti-COPB1 Antikörper

Target: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QLALDLVSSR NVEELVIVLK KEVIKTNNVS EHEDTDKYRQ LLVRTLHSCS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against COPB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human COPB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 953 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-COPB1 Antikörper (ABIN2784899)

Goryachev, Pokhilko: "Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes." in: PLoS computational biology, Vol. 2, Issue 12, pp. e172, (2007) (PubMed).

Details zu COPB1

Target: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Andere Bezeichnung: COPB1 (COPB1 Produkte)

Synonyme: id:ibd5034 antikoerper, wu:fc66c05 antikoerper, zgc:92482 antikoerper, COPB1 antikoerper, DKFZp459K154 antikoerper, COPB antikoerper, 2610019B04Rik antikoerper, Rack2 antikoerper, Beta-COP antikoerper, coatomer protein complex, subunit beta 1 antikoerper, coatomer protein complex subunit beta 1 L homeolog antikoerper, coatomer protein complex subunit beta 1 antikoerper, copb1 antikoerper, copb1.L antikoerper, COPB1 antikoerper, Copb1 antikoerper

Hintergrund: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Alias Symbols: COPB, DKFZp761K102, FLJ10341
Protein Interaction Partner: SUMO2, NUDCD1, UBC, RNF2, EZH2, KLC1, DIAPH1, ARCN1, ACACA, COPG1, COPZ1, TLE3, FBXO6, UBD, KCNK3, KCNK9, NPM1, HDAC10, ERBB2IP, SNTA1, LZTS2, VPS18, NUB1, SERTAD1, FOXB1, IRAK3, TANK, ID1, HLA-DPB1, GRB2, XRCC6, FN1, CFTR, FMNL1, COPG2, COPE, COPB2, COPA
Protein Size: 953

Molekulargewicht: 107 kDa

Gen-ID: 1315

NCBI Accession: NM_016451, NP_057535

UniProt: P53618