TSEN15 Antikörper (C-Term)

Produktnummer ABIN2784943

Produktdetails anti-TSEN15 Antikörper

Target: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSEN15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ASLSHNRIRE ILKASRKLQG DPELPMSFTL AIVESDSTIV YYKLTDGFML

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Tsen15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 168 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TSEN15

Target: TSEN15 (tRNA Splicing Endonuclease 15 Homolog (TSEN15))

Andere Bezeichnung: Tsen15 (TSEN15 Produkte)

Synonyme: 5730449L18Rik antikoerper, AL023077 antikoerper, Sen15 antikoerper, C1orf19 antikoerper, sen15 antikoerper, tRNA splicing endonuclease subunit 15 antikoerper, Tsen15 antikoerper, TSEN15 antikoerper

Hintergrund: Tsen15 is a non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body. The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3' end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3' end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events.
Alias Symbols: 5730449L18Rik, AL023077, Sen15
Protein Interaction Partner: Eed,
Protein Size: 168

Molekulargewicht: 18 kDa

Gen-ID: 66637

NCBI Accession: NM_025677, NP_079953

UniProt: Q8R3W5