STARD4 Antikörper (Middle Region)

Produktnummer ABIN2785040

Produktdetails anti-STARD4 Antikörper

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STARD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CCVMRYTTAG QLWNIISPRE FVDFSYTVGY KEGLLSCGIS LDWDEKRPEF

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against STARD4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human STARD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 205 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STARD4

Target: STARD4 (StAR-Related Lipid Transfer (START) Domain Containing 4 (STARD4))

Andere Bezeichnung: STARD4 (STARD4 Produkte)

Synonyme: 4632419C16Rik antikoerper, 9030213J02Rik antikoerper, AA517649 antikoerper, AW324468 antikoerper, StAR related lipid transfer domain containing 4 antikoerper, StAR-related lipid transfer (START) domain containing 4 antikoerper, STARD4 antikoerper, Stard4 antikoerper

Hintergrund: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
Alias Symbols: -
Protein Interaction Partner: UBC,
Protein Size: 205

Molekulargewicht: 23 kDa

Gen-ID: 134429

NCBI Accession: NM_139164, NP_631903

UniProt: Q96DR4