CDC42EP5 Antikörper (Middle Region)

Produktnummer ABIN2785099

Produktdetails anti-CDC42EP5 Antikörper

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC42EP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HVGRGGDAFG DTSFLSRHGG GPPPEPRAPP AGAPRSPPPP AVPQSAAPSP

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC42EP5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC42EP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 148 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC42EP5

Target: CDC42EP5 (CDC42 Effector Protein (Rho GTPase Binding) 5 (CDC42EP5))

Andere Bezeichnung: CDC42EP5 (CDC42EP5 Produkte)

Synonyme: Borg3 antikoerper, CEP5 antikoerper, 1700027J19Rik antikoerper, 2010007O02Rik antikoerper, C85526 antikoerper, CDC42 effector protein 5 antikoerper, CDC42 effector protein (Rho GTPase binding) 5 antikoerper, CDC42EP5 antikoerper, Cdc42ep5 antikoerper

Hintergrund: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. The specific function of this protein has not yet been determined.
Alias Symbols: Borg3, CEP5, MGC21945, MGC71153
Protein Interaction Partner: SEPT7, CDC42, Sept6, Sept2,
Protein Size: 148

Molekulargewicht: 15 kDa

Gen-ID: 148170

NCBI Accession: NM_145057, NP_659494

UniProt: Q6NZY7

Pathways: Regulation of Actin Filament Polymerization