TRAF3IP2 Antikörper (N-Term)

Produktnummer ABIN2785129

Produktdetails anti-TRAF3IP2 Antikörper

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IPVEVDESEP YPSQLLKPIP EYSPEEESEP PAPNIRNMAP NSLSAPTMLH

Homologie: Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TRAF3IP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRAF3IP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 574 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Andere Bezeichnung: TRAF3IP2 (TRAF3IP2 Produkte)

Synonyme: ACT1 antikoerper, C6orf2 antikoerper, C6orf4 antikoerper, C6orf5 antikoerper, C6orf6 antikoerper, CIKS antikoerper, PSORS13 antikoerper, AI429613 antikoerper, Act1 antikoerper, RGD1304768 antikoerper, C6ORF4 antikoerper, t3jam antikoerper, traf3ip2 antikoerper, TRAF3IP2 antikoerper, MGC134034 antikoerper, TRAF3 interacting protein 2 antikoerper, Traf3 interacting protein 2 antikoerper, adapter protein CIKS antikoerper, TRAF3 interacting protein 2 L homeolog antikoerper, TRAF3IP2 antikoerper, Traf3ip2 antikoerper, LOC100473939 antikoerper, traf3ip3.L antikoerper, traf3ip3 antikoerper

Hintergrund: This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene.
Alias Symbols: ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581, PSORS13
Protein Interaction Partner: RIMBP3, IL17RA, MRPL28, STK16, UBE2V1, TRIP6, TRAF6, SYK, SRSF1, FHL3, ELAVL1, TRAF2, FBXW11, BTRC, UBC, Dlg4, TBK1, IKBKE, TNFRSF13C, TRAF3, CD40, MAP3K7, TRAF3IP2, IKBKG, IKBKB, CHUK, IL17A, MDFI, TRAF5, TRAF1,
Protein Size: 574

Molekulargewicht: 65 kDa

Gen-ID: 10758

NCBI Accession: NM_147200, NP_671733

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response