FBXO32 Antikörper (N-Term)

Produktnummer ABIN2785130

Produktdetails anti-FBXO32 Antikörper

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO32 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QQQLNNIQIT RPAFKGLTFT DLPLCLQLNI MQRLSDGRDL VSLGQAAPDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO32. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO32

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 210 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO32

Target: FBXO32 (F-Box Protein 32 (FBXO32))

Andere Bezeichnung: FBXO32 (FBXO32 Produkte)

Synonyme: MGC56479 antikoerper, zgc:56479 antikoerper, Fbx32 antikoerper, MAFbx antikoerper, 4833442G10Rik antikoerper, AI430017 antikoerper, ATROGIN1 antikoerper, Gm20361 antikoerper, Atrogin1 antikoerper, F-box protein 32 antikoerper, fbxo32 antikoerper, FBXO32 antikoerper, Fbxo32 antikoerper

Hintergrund: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Alias Symbols: FLJ32424, Fbx32, MAFbx, MGC33610
Protein Interaction Partner: UBC, MLH1, Mutyh, UBE2D3, KHDRBS3, SERPINB5, CDC34, DUSP1, FBXO25, MYBPC3, CDKN1A, EIF3F, SKP1, EIF3A,
Protein Size: 210

Molekulargewicht: 25 kDa

Gen-ID: 114907

NCBI Accession: NM_148177, NP_680482

UniProt: Q0VAQ6