GRPEL2 Antikörper (Middle Region)

Produktnummer ABIN2785166

Produktdetails anti-GRPEL2 Antikörper

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRPEL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HEHELICHVP AGVGVQPGTV ALVRQDGYKL HGRTIRLARV EVAVESQRRL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GRPEL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRPEL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 225 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRPEL2

Target: GRPEL2 (GrpE-Like 2, Mitochondrial (GRPEL2))

Andere Bezeichnung: GRPEL2 (GRPEL2 Produkte)

Synonyme: mt-GrpE2 antikoerper, mt-Grpel2 antikoerper, Afap1l1 antikoerper, Mt-GrpE2 antikoerper, GrpE-like 2, mitochondrial antikoerper, GrpE like 2, mitochondrial antikoerper, Grpel2 antikoerper, GRPEL2 antikoerper

Hintergrund: GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
Alias Symbols: DKFZp451C205, FLJ23713, FLJ33918, Mt-GrpE#2
Protein Interaction Partner: ELAVL1, UBC, HSPA4,
Protein Size: 225

Molekulargewicht: 25 kDa

Gen-ID: 134266

NCBI Accession: NM_152407, NP_689620

UniProt: Q8TAA5