C14orf49 antikoerper, NET53 antikoerper, Nesp3 antikoerper, 4831426I19Rik antikoerper, nesprin-3 antikoerper, spectrin repeat containing nuclear envelope family member 3 antikoerper, spectrin repeat containing, nuclear envelope family member 3 antikoerper, SYNE3 antikoerper, Syne3 antikoerper
Hintergrund
SYNE3 is a component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. It is involved in the maintenance of nuclear organization and structural integrity. It is a probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. SYNE3 plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells. Protein Size: 596