ZCCHC12 Antikörper (N-Term)

Produktnummer ABIN2785325

Produktdetails anti-ZCCHC12 Antikörper

Target: ZCCHC12 (Zinc Finger, CCHC Domain Containing 12 (ZCCHC12))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Kaninchen, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZCCHC12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AREVMRVLQA TNPNLSVADF LRAMKLVFGE SESSVTAHGK FFNTLQAQGE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ZCCHC12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 402 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZCCHC12

Target: ZCCHC12 (Zinc Finger, CCHC Domain Containing 12 (ZCCHC12))

Andere Bezeichnung: ZCCHC12 (ZCCHC12 Produkte)

Synonyme: PNMA7A antikoerper, SIZN antikoerper, SIZN1 antikoerper, 2810028A01Rik antikoerper, AV136720 antikoerper, Sizn1 antikoerper, zinc finger CCHC-type containing 12 antikoerper, sterile alpha motif domain containing 12 antikoerper, zinc finger, CCHC domain containing 12 antikoerper, ZCCHC12 antikoerper, samd12 antikoerper, Zcchc12 antikoerper

Hintergrund: ZCCHC12 contains 1 CCHC-type zinc finger. ZCCHC12 is the transcriptional coactivator in the bone morphogenetic protein (BMP)-signaling pathway. It positively modulates BMP signaling by interacting with SMAD1 and associating with CBP in the transcription complex. It contributes to the BMP-induced enhancement of cholinergic-neuron-specific gene expression.
Alias Symbols: FLJ16123, SIZN, SIZN1, PNMA7A
Protein Interaction Partner: PNMA1, SUMO1, TFCP2, MAGEA11, SUMO2, APP, SMAD1, CREBBP, UBC, APPBP2,
Protein Size: 402

Molekulargewicht: 45 kDa

Gen-ID: 170261

NCBI Accession: NM_173798, NP_776159

UniProt: Q6PEW1