LRRC50 Antikörper (N-Term)

Produktnummer ABIN2785360

Produktdetails anti-LRRC50 Antikörper

Target: LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRRC50 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LNDTLYLHFK GFDRIENLEE YTGLRCLWLQ SNGIQKIENL EAQTELRCLF

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LRRC50. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LRRC50

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 725 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LRRC50 Antikörper (ABIN2785360)

Basten, Davis, Gillis, van Rooijen, Stoop, Babala, Logister, Heath, Jonges, Katsanis, Voest, van Eeden, Medema, Ketting, Schulte-Merker, Looijenga, Giles: "Mutations in LRRC50 predispose zebrafish and humans to seminomas." in: PLoS genetics, Vol. 9, Issue 4, pp. e1003384, (2013) (PubMed).

Yang, Zhou, Ma, Wang, Chen, Meng, Yu, Zhou, Sun: "Knockdown of PPAR δ gene promotes the growth of colon cancer and reduces the sensitivity to bevacizumab in nude mice model." in: PLoS ONE, Vol. 8, Issue 4, pp. e60715, (2013) (PubMed).

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu LRRC50

Target: LRRC50 (Leucine Rich Repeat Containing 50 (LRRC50))

Andere Bezeichnung: LRRC50 (LRRC50 Produkte)

Hintergrund: LRRC50 contains 6 LRR (leucine-rich) repeats. It is proposed that LRRC50 to be a novel candidate gene for human cystic kidney disease, involved in regulation of microtubule-based cilia and actin-based brush border microvilli.
Alias Symbols: DKFZp434A119, FLJ25330, ODA7, CILD13, LRRC50
Protein Interaction Partner: UBC,
Protein Size: 725

Molekulargewicht: 80 kDa

Gen-ID: 123872

NCBI Accession: NM_178452, NP_848547

UniProt: Q8NEP3